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Description about Reglan.

Reglan is in a class of drugs called prokinetic agents.which work by increasing muscle contractions in the upper digestive tract to speed up movement through the stomach and intestines.

It is estimated that approximately 5 million people in the United States are affected by gastroparesis.

The management of NMS should include 1) immediate discontinuation of metoclopramide and other drugs not essential to concurrent therapy.2) intensive symptomatic treatment and medical monitoring.and 3) treatment of any concomitant serious medical problems for which specific treatments are available. Bromocriptine and dantrolene sodium have been used in treatment of NMS.but their effectiveness have not been established (see ADVERSE REACTIONS).

Metoclopramide should not be used whenever stimulation of gastrointestinal motility might be dangerous.e.g..in the presence of gastrointestinal hemorrhage.mechanical obstruction.or perforation.

Frequency not reported . Acute asthmatic symptoms.bronchospasm.laryngeal edema.respiratory failure.wheezing [Ref]

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